Study shows a single serving of Ambrotose® complex enhances memory
February 12, 2014

In a double-blind, placebo-controlled human clinical trial published in Nutritional Neuroscience, healthy middle-aged adults who consumed Ambrotose complex powder showed significant improvements in tests measuring recognition and memory compared with subjects taking a placebo or sucrose.*(1) According to the study authors, this is the “first report of acute behavioural improvement following plant polysaccharide intake in healthy middle-aged adults under conditions of mental fatigue. The findings suggest that certain NSP** may enhance memory performance through mechanisms other than elevated blood glucose.” Previous studies have reported similar benefits following 12 weeks of intake of Ambrotose complex (2),(3).

The study was conducted by Dr. Talitha Best, a post-doctoral research fellow at the Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia (UniSA), Dr. Peter Howe of the Clinical Nutrition Research Centre, University of Newcastle, Newcastle, Australia, Dr. Janet Bryan, School of Psychology, Social Work and Policy, University of South Australia, Adelaide, Australia, Dr. Jonathan Buckley of the Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia and Andrew Scholey of the Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, Australia.***



Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults


Link to publication

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
** NSP= non-starch polysaccharides
***Mannatech provided partial funding and provided the Ambrotose supplement and placebo used in this study.

  1. Best T, Howe P, Bryan J, Buckley J, Scholey A. Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults. Nutr Neurosci 2014;1-11.
  2. Best T, Kemps E, Bryan J. Saccharide effects on cognition and well-being in middle-aged adults: A randomized controlled trial. Dev Neuropsych 2010;35:66-80.
  3. Best T. An investigation of saccharide effects on memory performance. Abstracts of the 12th Annual Australian Psch Conf 2005;57.